Crohn's disease symptoms can vary based on where the swelling is and how severe it is. The most common symptoms are diarrhea, cramping and pain in your belly, and weight loss. Other possible symptoms include fatigue, fever, joint pain, nausea, and loss of appetite. Some people also notice eye redness or skin changes, like red tender bumps. Stress and certain foods — such as carbonated drinks and high-fiber foods — may make symptoms worse for some people. Let your care team know if anything changes.